Direktorat Jenderal Pengawasan Obat dan Makanan 2000. Parameter Standar Umum Ekstrak Tumbuhan Obat. Universitas Surabaya 2008.ĭepartemen Kesehatan Republik Indonesia. Lumowa D., Antimalaria Ekstrak Etanol Batang Brotowali (Tinospora Crispa Diels) Secara In Vivo. Kupang Nusa Tenggara Timur, Jurnal Kedokteran Brawijaya 2014. Uji Anti Plasmodium Ekstrak Batang Tinospora crispa terhadap Plasmodium falciparum Galur 3 D7 secara In Vitro. Efek Antimalaria ekstrak Brotowali (Tinospora crispa) pada mencit yang diinfeksiPlasmodium berghei. Monografi Ekstrak Tumbuhan Obat Indonesia. Jakarta 2013.īadan Pengawasan Obat dan Makanan Republik Indonesia. Pedoman Teknologi Formulasi Sediaan Berbasis Ekstrak Volume 2. 3-14.īadan Pengawasan Obat dan Makanan Republik Indonesia. Jakarta : Direktorat Jenderal Pengendalian Penyakit dan Penyehatan Lingkungan 2006. Pedoman Penatalaksaan Kasus Malaria di Indonesia. Article Detailsĭepartemen Kesehatan Republik Indonesia. The conclusions of this research are extracted Caulis tablet can be created that meets the requirements of physical quality test tablet. The results showed that the two formula tablets with the uniformity of weight, hardness, size uniformity, compressibility, and the time crushed tablet that meets the requirements of the physical quality of a good tablet. The data obtained were analyzed statistically using SPSS 15.0 for windows program namely testing T-Test with a 5% confidence. Tablets obtained physical quality test performed which include uniformity of weight, hardness, size uniformity, compressibility, and the crushed tablets. Granul tested his physical properties obtained covering moist, flow properties, compressibility granule. The methods used in the manufacture of Caulis extract tablets using a wet granulation method. Caulis extract tablet manufacture is made with two formula with each different binding materials, namely formula I used gelatin formula II 5% and 5% use polivinilpirolidon. Prior to the manufacture of tablets do extract raw materials testing which includes the determination of the levels of ash, determination of microbial impurities, testing the determination of aflatoxin levels of impurities, the determination of the levels of pesticide residues, the determination of the level of heavy metal impurities. This research aims to make the tablet dosage of Caulis extract with gelatin Binder and polivenilpirolidon materials that meet the requirements of the physical quality of a tablet that is acceptable. The entire plant (roots, stems, and leaves) has a bitter taste that can be used as a traditional medicine as Plasmodium. Thomson is a wild plant & in the Woods, fields or planted page near the fence, and the usual planted as medicinal plants.
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